Bookmakers BET365 have offered odds of 9/4 for the Sky Blues to win with Plymouth 5/4. You can get 9/4 on a draw.
City's last win was an FA Cup win in January 1996. They have also won in friendlies in the 1990s.
Saturday's game at Home Park is the 45th meeting of the two sides with Coventry having won 17 of those games. There has been eight draws. City have scored 62 goals compared to Argyle's 72.