"The onus is always on the home side infront of a home crowd because there is always a pressure to perform and entertain your fans. We know that," said Chris Coleman to the club website.
"QPR came to the Ricoh earlier on this season and while they had the majority of the attacking play in the second half, we got the better of the first 45 minutes so it will be an interesting game.
"But Rangers are one of those sides you can never take lightly. Loftus Road is a difficult place to go to and we've got to go there and try our best to bring something back."
QPR have been busy since the transfer window opened and are likely to have Wayne Routledge, signed from Aston Villa in their starting line up. Heidar Helguson could also play but former Sky Blue Gary Borrowdale is not expected to feature.